Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121517 | 0.85 | NR4A2 (0.40) | NR4A2SLC40A1RAB9ATP53KLF5 | |
| SCHEMBL13689202 | 0.82 | APEX1 (0.33) | SLC40A1APEX1EGLN1RAB9ASMN1; SMN2 | |
| SCHEMBL3131699 | 0.82 | NR4A2 (0.43) | NR4A2RAB9ATP53KLF5SMN1; SMN2 | |
| SCHEMBL3129635 | 0.74 | NR4A2 (0.38) | NR4A2RAB9ATP53KLF5SMN1; SMN2 | |
| SCHEMBL568902 | 0.73 | C3AR1 (0.36) | APEX1EGLN1RAB9ASMN1; SMN2HPGDS | |
| SCHEMBL24158855 | 0.63 | NR4A2 (0.40) | NR4A2RAB9ATP53KLF5SMN1; SMN2 | |
| SCHEMBL15296578 | 0.63 | EGLN1 (0.35) | EGLN1RAB9ASMN1; SMN2HPGDSALDH1A1 | |
| SCHEMBL15296576 | 0.63 | EGLN1 (0.35) | EGLN1HPGDSALDH1A1 | |
| SCHEMBL8340106 | 0.62 | RAB9A (0.73) | RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL19545598 | 0.62 | ALPG (0.55) | APEX1RAB9ATP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |