SCHEMBL31296474

SCHEMBL31296474

CCCCCc1ccc2c(c1)CC(C(=O)OC)(C(=O)OC)C2

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.45
PPARG P37231 1/20 0.45
SPHK1 Q9NYA1 6/20 0.43
SPHK2 Q9NRA0 3/20 0.43
KAT8 Q9H7Z6 2/20 0.42
ALDH1A1 P00352 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
S1PR1 P21453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259420 0.84 PLK1 (0.39) PPARAPPARGSPHK1SPHK2ALDH1A1
SCHEMBL31296493 0.82 MMP8 (0.46) ALDH1A1
SCHEMBL22018267 0.72 KDM4E (0.40) ALDH1A1
SCHEMBL31296443 0.71 MEN1 (0.35) PPARAPPARGALDH1A1
SCHEMBL13259217 0.70 CYP4F2 (0.45)
SCHEMBL22400674 0.69 BACE1 (0.37)
SCHEMBL31296495 0.68 MAOA (0.36) PPARAALDH1A1
SCHEMBL28773091 0.68 PPARA (0.58) PPARAPPARGKAT8ALDH1A1
SCHEMBL19996369 0.68 SLC6A2 (0.50) PPARAKAT8ALDH1A1S1PR1
SCHEMBL2930325 0.68 HTR2A (0.52) PPARAKAT8ALDH1A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed