Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 5/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 5/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994372 | 0.82 | HTR2A (0.56) | HTR2ACA1CA2GPR3TDO2 | |
| SCHEMBL7576966 | 0.74 | HTR2A (0.64) | HTR2ACA1CA2GPR3TDO2 | |
| SCHEMBL2069075 | 0.74 | HTR2A (0.52) | HTR2ACA1CA2GPR3TDO2 | |
| SCHEMBL1776672 | 0.70 | HTR2A (0.58) | HTR2ACA1CA2GPR3TDO2 | |
| SCHEMBL4698772 | 0.70 | GPR3 (0.37) | HTR2AMIFTRPA1ALDH1A1CYP3A4 | |
| SCHEMBL2068350 | 0.69 | CA1 (0.49) | HTR2ACA1CA2GPR3TDO2 | |
| SCHEMBL5353138 | 0.69 | HTR2A (0.64) | HTR2ACYP3A4CA1CA2GPR3 | |
| SCHEMBL7574105 | 0.67 | HTR2A (0.61) | HTR2ACYP3A4CA1CA2GPR3 | |
| SCHEMBL17022715 | 0.67 | HTR2A (0.61) | HTR2ACYP3A4CA1CA2GPR3 | |
| SCHEMBL3073670 | 0.67 | HTR2A (0.54) | HTR2ACYP3A4CA1CA2GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805280-B | Heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-12-06 | — | — | CN | disclosed |