Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 16/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297590 | 0.85 | MET (0.43) | TGFBR1CCNCCDK8DYRK1AMAPK14 | |
| SCHEMBL31324863 | 0.84 | TGFBR1 (0.38) | TGFBR1DYRK1A | |
| SCHEMBL31324903 | 0.83 | TGFBR1 (0.43) | TGFBR1CCNCCDK8DYRK1ASCN5A | |
| SCHEMBL31297692 | 0.82 | TGFBR1 (0.42) | TGFBR1DYRK1ASCN5A | |
| SCHEMBL31297607 | 0.81 | TGFBR1 (0.44) | TGFBR1DYRK1ASCN5AMAPK14 | |
| SCHEMBL31297619 | 0.79 | TGFBR1 (0.42) | TGFBR1DYRK1A | |
| SCHEMBL31297576 | 0.78 | DYRK1A (0.43) | TGFBR1DYRK1ASCN5AMAPK14 | |
| SCHEMBL31297716 | 0.77 | CCNC (0.44) | CCNCCDK8DYRK1AMAPK14 | |
| SCHEMBL31297653 | 0.70 | CCNC (0.36) | CCNCCDK8 | |
| SCHEMBL31297553 | 0.67 | CLK2 (0.45) | CCNCCDK8DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |