Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736658 | 1.00 | PGR (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2736657 | 1.00 | PGR (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3128781 | 0.91 | PGR (0.49) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11151429 | 0.84 | PARP10 (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11230623 | 0.84 | PGR (0.49) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11574087 | 0.82 | CHRM2 (0.54) | ADRA2BLMNAALDH1A1GSK3BTDP1 | |
| SCHEMBL2736655 | 0.81 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2736656 | 0.81 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL14665678 | 0.81 | PGR (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2128162 | 0.81 | PGR (0.58) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101619056-B | Benzothiophene alkanol piperazine derivatives and use thereof as antidepressant medicaments | SHANGHAI INST PHARM INDUSTRY | 2013-07-17 | — | — | CN | disclosed |
| EP-1256569-B1 | PHENACYLAMINE DERIVATIVES, PRODUCTION THEREOF AND PEST CONTROLLERS CONTAINING THE DERIVATIVES | ISHIHARA SANGYO KAISHA (JP) | 2010-07-07 | — | — | EP | disclosed |
| CN-101619056-A | Benzothiophene alkanol piperazine derivatives and use thereof as antidepressant medicaments | ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD | 2010-01-06 | — | — | CN | disclosed |
| US-7439366-B2 | Phenacylamine derivatives, process for their production and pesticides containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20030153464-A1 | Phenacylamin derivatives, production thereof and pest controllers containing the derivatives | ISHIHARA SANGYO KAISHA LTD. (JP) | 2003-08-14 | — | — | US | disclosed |
| EP-1256569-A1 | PHENACYLAMINE DERIVATIVES, PRODUCTION THEREOF AND PEST CONTROLLERS CONTAINING THE DERIVATIVES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-5179229-A | Preparation of 2,2-diorgano-3-arylpropionic acids and esters thereof | HOECHST CELANESE CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-RE30634-E | INSECTICIDES | SHELL OIL COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4108897-A | Benzylhydroxylamine ethers | SHELL OIL COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4079149-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153464-A1 | Phenacylamin derivatives, production thereof and pest controllers containing the derivatives | SCN4A, NAT1, HCN4 | PGR 3672/4885ADRA2A 688/4885ADRA2B 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.