SCHEMBL31297935

SCHEMBL31297935

COc1cc2c(cc1C=O)Sc1ccccc1N2C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.51
NOX1 Q9Y5S8 5/20 0.48
L3MBTL1 Q9Y468 5/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ADRA2A P08913 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
CHRM3 P20309 1/20 0.48
SLC6A2 P23975 1/20 0.48
HTR2C P28335 1/20 0.48
SLC6A4 P31645 1/20 0.48
DRD3 P35462 1/20 0.48
HTR2B P41595 1/20 0.48
MAPT P10636 6/20 0.47
LMNA P02545 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPK1 P28482 1/20 0.47
BCHE P06276 2/20 0.43
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758571 0.84 MAOA (0.63) MAOANOX1L3MBTL1MEN1KMT2A
SCHEMBL29067124 0.84 MEN1 (0.48) MEN1KMT2AADRA2ADRD3MAPT
SCHEMBL28863743 0.83 MAPT (0.44) MEN1KMT2AADRA2ADRD3MAPT
SCHEMBL31020994 0.82 KDM1A (0.48) MEN1KMT2AADRA2AADRA2BADRA2C
SCHEMBL31297936 0.81 MAOA (0.54) MAOANOX1L3MBTL1MEN1KMT2A
SCHEMBL7392294 0.74 MAOA (0.56) MAOANOX1L3MBTL1MEN1KMT2A
SCHEMBL1418367 0.74 MAOA (0.61) MAOANOX1L3MBTL1MEN1KMT2A
Formic Acid SCHEMBL8501926 0.72 MAOA (0.76) MAOANOX1L3MBTL1MEN1KMT2A
SCHEMBL31297952 0.72 MAOA (0.63) MAOANOX1L3MBTL1MEN1KMT2A
SCHEMBL7123151 0.72 SNCA (0.69) MAOANOX1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241527-A Fluorescent probe based on phenothiazine structure and preparation method thereof 中北大学 2025-01-03 CN disclosed