SCHEMBL7123151

SCHEMBL7123151

COc1ccc2c(c1)Sc1ccccc1N2C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 4/20 0.69
MAOA P21397 1/20 0.63
L3MBTL1 Q9Y468 4/20 0.61
NOX1 Q9Y5S8 3/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ADRA2A P08913 1/20 0.61
ADRA2B P18089 1/20 0.61
ADRA2C P18825 1/20 0.61
CHRM3 P20309 1/20 0.61
SLC6A2 P23975 1/20 0.61
HTR2C P28335 1/20 0.61
SLC6A4 P31645 1/20 0.61
DRD3 P35462 1/20 0.61
HTR2B P41595 1/20 0.61
KDM4E B2RXH2 3/20 0.57
MAPK1 P28482 2/20 0.57
TP53 P04637 1/20 0.57
MAPT P10636 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7389154 0.91 SNCA (0.81) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL31297952 0.90 MAOA (0.63) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL7124233 0.90 MAOA (0.63) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL8132434 0.83 MAOA (0.54) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL8907377 0.83 MAPK1 (0.60) SNCAL3MBTL1NOX1MEN1KMT2A
SCHEMBL27379496 0.83 MAOA (0.58) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL2760350 0.83 SNCA (0.64) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL9639556 0.80 SNCA (0.61) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL4758571 0.80 MAOA (0.63) SNCAMAOAL3MBTL1NOX1MEN1
SCHEMBL231247 0.80 MAOA (1.00) MAOAL3MBTL1NOX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
JP-2000512267-A 2000-09-19 JP claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed
US-20090303855-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2009-12-10 US disclosed
US-20090303855-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2009-12-10 US disclosed
US-6660503-B2 In aqueous solution NOVOZYMES A/S (DK) 2003-12-09 US disclosed
EP-0935692-B1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVOZYMES AS (DK) 2002-11-27 EP disclosed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US disclosed
EP-0912097-B1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVOZYMES AS (DK) 2002-08-07 EP disclosed
EP-0787230-B1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVOZYMES AS (DK) 2002-03-20 EP disclosed
US-6346401-B1 OXIDATION OF HYDROXY GROUP OF SUGAR MONOMER OF STARCH BY CONTACTING WITH PEROXIDASE, HYDROGEN PEROXIDE AND ENHANCING AGENT IN AQUEOUS MEDIUM; FORMS CARBONYL OR CARBOXYLATE GROUP NOVOZYMES A/S (DK) 2002-02-12 US disclosed
WO-1997040229-A1 FABRIC TREATED WITH A CELLULASE AND A HYBRID ENZYME COMPRISING A PHENOL OXIDIZING ENZYME NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997040127-A1 BLEACHING OF FABRIC WITH A HYBRID ENZYME CONTAINING A PHENOL OXIDIZING ENZYME FUSED TO A CELLULOSE BINDING DOMAIN NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 WO disclosed
EP-0195582-B1 5-AMINOSALICYLIC ACID DERIVATIVES OF NON-STEROIDAL ANTIINFLAMMATORY ACIDS SMITH KLINE DAUELSBERG GmbH (DE) 1990-01-24 EP disclosed
US-4851443-A NON-STEROIDAL ANTIINFLAMMATORY; DERIVATIVES OF 5-AMINOSALICYLIC ACID SMITH KLINE DAUELSBERG, GMBH (DE) 1989-07-25 US disclosed
US-4783487-A N-(1-carboxy-2-hydroxy-5-phenyl)-2-(6-methoxy-2-naphthyl)propionamide and anti-inflammatory use thereof SMITH KLINE DAUELSBERG GMBH (DE) 1988-11-08 US disclosed
WO-1986005485-A1 AMIDES OF NON-STEROIDAL ANTI-INFLAMMATORY CARBOXYLIC ACIDS SMITH KLINE DAUELSBERG GMBH (DE) 1986-09-25 WO disclosed
EP-0195582-A1 5-Aminosalicylic acid derivatives of non-steroidal antiinflammatory acids SMITH KLINE DAUELSBERG GmbH (DE) 1986-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 SNCA 3122/4885MAOA 1245/4885L3MBTL1 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.