Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012255 | 0.88 | KDM4E (0.64) | KDM4EKMT2A | |
| SCHEMBL31297979 | 0.80 | KDM4E (0.78) | KDM4EKMT2A | |
| SCHEMBL17197604 | 0.75 | — | — | |
| SCHEMBL16750982 | 0.74 | KDM4E (0.69) | KDM4EKMT2A | |
| SCHEMBL21661359 | 0.73 | KDM4E (0.38) | KDM4EKMT2A | |
| SCHEMBL13990474 | 0.73 | KDM4E (0.38) | KDM4EKMT2A | |
| SCHEMBL29640099 | 0.73 | KDM4E (0.38) | KDM4EKMT2A | |
| SCHEMBL18828746 | 0.73 | KDM4E (0.47) | KDM4EKMT2A | |
| SCHEMBL6867738 | 0.72 | KDM4E (0.67) | KDM4EKMT2A | |
| SCHEMBL21916708 | 0.72 | KDM4E (0.39) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | MILLENNIUM PHARM INC (US) | 2025-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | WNT1, XPOT, CTNNBL1 | KDM4E 2279/4885KMT2A 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.