Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31298071 | 0.85 | GAA (0.43) | GAAALOX5RAB9AACHEDRD4 | |
| SCHEMBL31298060 | 0.83 | SIGMAR1 (0.58) | GAASIGMAR1GPR6ALOX5MEN1 | |
| SCHEMBL12152000 | 0.79 | HRH4 (0.46) | HRH4SIGMAR1ADRB1RENKMT2A | |
| SCHEMBL1090206 | 0.79 | SIGMAR1 (0.65) | HRH4SIGMAR1RENKMT2AACHE | |
| SCHEMBL1090204 | 0.79 | SIGMAR1 (0.65) | HRH4SIGMAR1RENKMT2AACHE | |
| SCHEMBL12151974 | 0.79 | HRH4 (0.46) | HRH4SIGMAR1ADRB1RENKMT2A | |
| SCHEMBL1733229 | 0.79 | HRH4 (0.46) | HRH4SIGMAR1ADRB1RENKMT2A | |
| SCHEMBL10293578 | 0.79 | SIGMAR1 (0.65) | HRH4SIGMAR1RENKMT2AACHE | |
| Hydrochloric Acid SCHEMBL3922069 | 0.77 | SIGMAR1 (0.63) | HRH4SIGMAR1RENKMT2AACHE | |
| Hydrochloric Acid SCHEMBL3922073 | 0.77 | SIGMAR1 (0.63) | HRH4SIGMAR1RENKMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | MILLENNIUM PHARM INC (US) | 2025-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | WNT1, XPOT, CTNNBL1 | HRH4 4216/4885GAA 4758/4885SIGMAR1 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.