Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.58 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.50 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996402 | 1.00 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL590225 | 0.86 | LMNA (0.58) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL29923390 | 0.86 | LMNA (0.58) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL25739731 | 0.82 | GRM4 (0.50) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8145365 | 0.81 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL2997568 | 0.80 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30682081 | 0.79 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL201122 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL11772078 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL3841526 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007113-A2 | MITOCHONDRIAL COMPLEX I INHIBITORS WITH REDUCED PHOSPHODIESTERASE INHIBITION | OHIO STATE INNOVATION FOUNDATION (US) | 2025-01-02 | — | — | WO | disclosed |