SCHEMBL31298640

SCHEMBL31298640

Cln1nc(C2CC2)c2cccnc21

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.38
GRM4 Q14833 3/20 0.36
CYP1A2 P05177 2/20 0.36
PDK2 Q15119 1/20 0.36
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
FEN1 P39748 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
KHK P50053 1/20 0.33
OPRL1 P41146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28317348 0.74 CYP11B2 (0.44) GRM4CYP1A2DDB1CRBNL3MBTL1
SCHEMBL30405634 0.72 FEN1 (0.40) CYP1A2DDB1CRBNL3MBTL1FEN1
SCHEMBL24329843 0.71 CYP1A2 (0.42) GRM4CYP1A2
Hydrochloric Acid SCHEMBL26911725 0.70 CYP1A2 (0.42) GRM4CYP1A2
SCHEMBL5262178 0.68 KMT2A (0.39) ELANECYP1A2L3MBTL1FEN1GABRA1
SCHEMBL364660 0.65 OPRL1 (0.57) OPRL1
Potassium SCHEMBL29930080 0.63 OPRL1 (0.56) OPRL1
SCHEMBL363270 0.62 PDK2 (0.47) CYP1A2PDK2OPRL1
SCHEMBL21733021 0.62 PDK2 (0.47) GRM4CYP1A2PDK2OPRL1
SCHEMBL1609990 0.61 FEN1 (0.56) ELANEGRM4CYP1A2L3MBTL1FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119156381-A Compounds and methods for treating cancer 上海睿跃生物科技有限公司 2024-12-17 CN disclosed