Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767482 | 0.80 | ACHE (0.40) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10958524 | 0.75 | CA1 (0.48) | CYP3A4MAPK1MAPTALDH1A1TDP1 | |
| SCHEMBL126505 | 0.72 | CA2 (0.54) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL31299834 | 0.70 | MAPT (0.52) | MAPK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7921161 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL3242947 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL8364747 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL8097041 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL2981226 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL5658673 | 0.70 | CA2 (0.52) | CYP3A4MAPK1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238570-A1 | CDK2 INHIBITOR PYRAZOLOPYRIMIDINE COMPOUNDS | ALEKSIA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |