Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863968 | 0.86 | LMNA (0.56) | CYP19A1MAPK1LMNAMAPTIDO1 | |
| SCHEMBL12234576 | 0.80 | MAPK1 (0.43) | MAPK1IDO1RAB9ASMN1; SMN2CYP11B1 | |
| SCHEMBL19556283 | 0.78 | CYP2A6 (0.53) | CYP19A1MAPK1LMNAMAPTKDM4E | |
| SCHEMBL4462212 | 0.77 | MAPK1 (0.46) | MAPK1IDO1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL10615865 | 0.77 | BCHE (0.47) | MAPK1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2253693 | 0.74 | RAB9A (0.46) | CYP19A1MAPK1LMNAMAPTIDO1 | |
| SCHEMBL30056169 | 0.74 | RAB9A (0.46) | CYP19A1MAPK1LMNAMAPTIDO1 | |
| SCHEMBL27736012 | 0.74 | MAPK1 (0.44) | MAPK1LMNAMAPTIDO1SMN1; SMN2 | |
| SCHEMBL17463148 | 0.74 | MAPK1 (0.44) | MAPK1LMNAMAPTIDO1RAB9A | |
| SCHEMBL7280526 | 0.73 | CYP19A1 (0.58) | CYP19A1LMNAMAPTSMN1; SMN2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737448-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | Artivila (ShenZhen) Innovation Center, Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002030-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-01-02 | — | — | WO | disclosed |