Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Levosalbutamol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 9/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levosalbutamol SCHEMBL29394399 | 1.00 | ADRB2 (0.82) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Levosalbutamol SCHEMBL1247104 | 1.00 | ADRB2 (0.82) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL4434233 | 1.00 | ADRB2 (0.82) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL6838948 | 0.92 | ADRB2 (0.87) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL122805 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL2489838 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Levosalbutamol SCHEMBL4003 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL4913 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| Albuterol SCHEMBL121596 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 | |
| (S)-Albuterol SCHEMBL29496690 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119269679-A | Method for detecting oleic acid in levosalbutamol tartrate inhalation aerosol | 山东达因海洋生物制药股份有限公司 | 2025-01-07 | — | — | CN | disclosed |