Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.62 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157529 | 0.98 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Hydrochloric Acid SCHEMBL31301131 | 0.96 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Bromide SCHEMBL31301132 | 0.96 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Hydrochloric Acid SCHEMBL20528844 | 0.96 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| SCHEMBL18331491 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Bromide SCHEMBL6116865 | 0.95 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Hydrochloric Acid SCHEMBL3120286 | 0.95 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Iodide SCHEMBL2254575 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| SCHEMBL192702 | 0.91 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KMT2AATMTGM2 | |
| Iodide SCHEMBL17105877 | 0.89 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | claimed |
| WO-2024254965-A1 | POLYELECTROLYTE GEL, PREPARATION METHOD THEREFOR AND USE THEREOF | 清华大学 | 2024-12-19 | — | — | WO | disclosed |