Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.62 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31301131 | 1.00 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Hydrochloric Acid SCHEMBL3120286 | 0.98 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| SCHEMBL5157529 | 0.98 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Bromide SCHEMBL31301132 | 0.96 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Iodide SCHEMBL31301133 | 0.96 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| SCHEMBL18331491 | 0.96 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Bromide SCHEMBL6116865 | 0.95 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2APEX1TGM2TSHR | |
| Hydrochloric Acid SCHEMBL127417 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Hydrochloric Acid SCHEMBL26669425 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 | |
| Hydrochloric Acid SCHEMBL31470991 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2APEX1NPSR1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12589377-B2 | Encapsulated composition comprising core-shell microcapsules and process for its preparation | GIVAUDAN SA (CH) | 2026-03-31 | — | — | US | disclosed |
| US-20250332085-A1 | RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2025-10-30 | — | — | US | disclosed |
| US-12409109-B2 | Dry mixture and personal care composition as well as methods for their production | WEIDMANN HOLDING AG (CH) | 2025-09-09 | — | — | US | disclosed |
| US-20250205138-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2025-06-26 | — | — | US | disclosed |
| EP-3852916-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2025-02-19 | — | — | EP | disclosed |
| US-20240382389-A1 | DRY MIXTURE AND PERSONAL CARE COMPOSITION AS WELL AS METHODS FOR THEIR PRODUCTION | WEIDMANN HOLDING AG (CH) | 2024-11-21 | — | — | US | disclosed |
| EP-3765159-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-05-08 | — | — | EP | disclosed |
| US-20230340374-A1 | Improvements in or Relating to Organic Compounds | GIVAUDAN SA (CH) | 2023-10-26 | — | — | US | disclosed |
| EP-4265237-A1 | HAIR CARE OR HAIR CLEANSING OR SKIN CARE OR SKIN CLEANSING COMPOSITION | Weidmann Holding AG (CH) | 2023-10-25 | — | — | EP | disclosed |
| EP-3606500-B1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2023-10-04 | — | — | EP | disclosed |
| US-20210085590-A1 | Improvements in or Relating to Organic Compounds | GIVAUDAN SA (CH) | 2021-03-25 | — | — | US | disclosed |
| EP-3765159-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2021-01-20 | — | — | EP | disclosed |
| US-20210007941-A1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2021-01-14 | — | — | US | disclosed |
| US-20200360243-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2020-11-19 | — | — | US | disclosed |
| EP-3687678-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2020-08-05 | — | — | EP | disclosed |
| WO-2020058044-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2020-03-26 | — | — | WO | disclosed |
| EP-3606500-A1 | PERSONAL CARE COMPOSITION | Weidmann Holding AG (CH) | 2020-02-12 | — | — | EP | disclosed |
| WO-2019175017-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019063515-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-04-04 | — | — | WO | disclosed |
| WO-2018185230-A1 | PERSONAL CARE COMPOSITION | WEIDMANN HOLDING AG (CH) | 2018-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12589377-B2 | Encapsulated composition comprising core-shell microcapsules and process for its preparation | CUTA, EXOC1, EXOSC10 | ACHE 194/4885ZDHHC20 850/4885ZDHHC2 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.