SCHEMBL31301317

SCHEMBL31301317

Cc1cc(Cl)ccc1N(C)C(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)n1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 12/20 0.47
SCN10A Q9Y5Y9 6/20 0.44
SCN2A Q99250 4/20 0.44
TACR1 P25103 2/20 0.39
TACR2 P21452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301565 0.91 SCN10A (0.43) GPBAR1SCN10ASCN2ATACR1TACR2
SCHEMBL31301292 0.89 SCN10A (0.41) GPBAR1SCN10ASCN2ATACR1TACR2
SCHEMBL31301571 0.89 SCN10A (0.44) GPBAR1SCN10ASCN2A
SCHEMBL31301288 0.88 SCN10A (0.45) GPBAR1SCN10ASCN2A
SCHEMBL31301372 0.88 GPBAR1 (0.43) GPBAR1SCN10ASCN2A
SCHEMBL31301335 0.87 SCN10A (0.44) GPBAR1SCN10ASCN2ATACR1TACR2
SCHEMBL31301360 0.84 GPBAR1 (0.53) GPBAR1SCN10ASCN2A
SCHEMBL31301655 0.82 SCN10A (0.43) GPBAR1SCN10ASCN2A
SCHEMBL31301449 0.81 SCN10A (0.41) GPBAR1SCN10ASCN2A
SCHEMBL31301408 0.79 SCN10A (0.56) SCN10ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS GPBAR1 803/4885SCN10A 3171/4885SCN2A 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.