Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128687 | 0.92 | MEN1 (0.56) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3128668 | 0.84 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL27810963 | 0.83 | MEN1 (0.61) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL209002 | 0.83 | MEN1 (0.86) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3125441 | 0.82 | MEN1 (0.64) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3130254 | 0.81 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL27810962 | 0.79 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3131442 | 0.77 | PTGES (0.51) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3131583 | 0.75 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3130156 | 0.75 | PTGES (0.43) | MEN1KMT2AMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164846-A2 | HETEROARYL SUBSTITUTED THIAZOLES AND THEIR USE AS ANTIVIRAL AGENTS. | Achillion Pharmaceuticals, Inc. (US) | 2010-03-24 | — | — | EP | claimed |
| WO-2008147557-A2 | HETEROARYL SUBSTITUTED THIAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-12-04 | — | — | WO | claimed |