Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.42 |
| ▸ | PPP5C | P53041 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268145 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13216620 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL196877 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27496 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL533614 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10050519 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13897083 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL12549702 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13957069 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13397502 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503857-B1 | RECYCLABLE CHIRAL METATHESIS CATALYSTS | TRUSTEES BOSTON COLLEGE (US) | 2010-07-07 | — | — | EP | disclosed |