SCHEMBL196877

SCHEMBL196877

O=C1OC(=O)[C@H]2C3C=CC(C3)[C@@H]12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
SMN1; SMN2 Q16637 4/20 0.42
RAB9A P51151 3/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GMNN O75496 1/20 0.42
PPM1B O75688 1/20 0.42
PPP1CC P36873 1/20 0.42
TFPI2 P48307 1/20 0.42
PPP5C P53041 1/20 0.42
PPP1CA P62136 1/20 0.42
PMP22 Q01453 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268145 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL13216620 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL3130301 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL27496 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL533614 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL10050519 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL13897083 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL12549702 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL13957069 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA
SCHEMBL13397502 1.00 ALDH1A1 (0.48) ALDH1A1TDP1SMN1; SMN2RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1072 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725937-A1 PROCESS FOR THE SYNTHESIS OF BICYCLIC CARBOXAMIDE COMPOUNDS Acousia Therapeutics GmbH (DE) 2026-04-15 EP claimed
US-20250026881-A1 CROSSLINKABLE FUNCTIONALIZED OLIGOESTERS AND POLYESTERS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY 2025-01-23 US claimed
US-20240327561-A1 FLUOROPOLYMER AND CYCLIC OLEFIN ALLOY DAIKIN AMERICA, INC. (US) 2024-10-03 US claimed
CN-118344793-A Anti-oxidation corrosion-resistant bus duct and preparation method thereof 广东宝士电气有限公司 2024-07-16 CN claimed
WO-2024147916-A1 VITRIMER OF CYCLOPENTENE-BASED RING-OPENING POLYOLEFIN ExxonMobil Technology and Engineering Company (US) 2024-07-11 WO claimed
CN-118048708-B Moisture-absorbing quick-drying polyester fiber and fabric 比音勒芬服饰股份有限公司 2024-06-14 CN claimed
CN-118048708-A Moisture-absorbing quick-drying polyester fiber and fabric 比音勒芬服饰股份有限公司 2024-05-17 CN claimed
CN-115611866-B Preparation method of tandospirone citrate 南京海纳医药科技股份有限公司 2024-04-23 CN claimed
CN-115894880-B Rigid polyester polyol and preparation method thereof 中欧电子材料国际创新中心(合肥)有限公司 2024-04-23 CN claimed
CN-117645854-B Multi-component polyacrylate adhesive and production method thereof 赢胜节能集团股份有限公司 2024-04-05 CN claimed
US-5073570-A MONO-IODOPROPARGYL ESTERS OF DICARBOXYLIC ANHYDRIDES AND THEIR USE AS ANTIMICROBIAL AGENTS LONZA INC. (US) 1991-12-17 US claimed
US-4980452-A Thermosettable prepolymers prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of Groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1990-12-25 US claimed
US-4927913-A Cured product from thermosettable prepolymer prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1990-05-22 US claimed
US-4847355-A Thermosettable prepolymer prepared from heterocyclic material having alkyl substituents, mono- or dianhydride, ethylenically unsaturated material and a hydroxide, carbonate of bicarbonate of a metal of groups I-A or II-A THE DOW CHEMICAL COMPANY (US) 1989-07-11 US claimed
US-4752636-A Thermosettable polymer or prepolymer prepared from heterocyclic materials containing nitrogen atoms, carboxylic acid mono- or dianhydrides and a polymerizable material with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1988-06-21 US claimed
US-4748255-A DIAMIC ACID OLIGOMER, POLYIMIDE FOAMS THERMAL SCIENCE, INC. (US) 1988-05-31 US claimed
US-4687785-A Thermally adaptive polymers and prepolymers and methods of making in which an imide is formed from a polyanhydride oligomer and an isocyanate THERMAL SCIENCE, INC. (US) 1987-08-18 US claimed
EP-0212652-A2 Thermally adoptive polymers and prepolymers and method of making them THERMAL SCIENCE, INC. (US) 1987-03-04 EP claimed
EP-0071749-B1 NOVEL POLYIMIDES AND POLYAMIC INTERMEDIATES THEREOF National Starch and Chemical Corporation (US) 1985-11-13 EP claimed
EP-0071749-A2 Novel polyimides and polyamic intermediates thereof National Starch and Chemical Corporation (US) 1983-02-16 EP claimed