Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 11/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496225 | 1.00 | GRM4 (0.45) | GRM4CYP1A2CYP2C19HCAR2AXL | |
| SCHEMBL12689594 | 0.81 | GRM4 (0.39) | GRM4AXLAURKAPARP1GPR84 | |
| SCHEMBL10154390 | 0.76 | GSK3B (0.37) | GRM4AXLAURKAPARP1GPR84 | |
| SCHEMBL13535278 | 0.75 | TRPV1 (0.39) | — | |
| SCHEMBL1639471 | 0.75 | AXL (0.41) | GRM4AXLAURKAPARP1GPR84 | |
| SCHEMBL19794531 | 0.73 | GRM4 (0.72) | GRM4CYP1A2CYP2C19 | |
| SCHEMBL24406204 | 0.73 | MAPT (0.39) | GRM4AXLGPR84 | |
| SCHEMBL1495296 | 0.72 | PDPK1 (0.48) | AXLAURKAPARP1GPR84LRRK2 | |
| SCHEMBL30631993 | 0.72 | PDPK1 (0.48) | AXLAURKAPARP1GPR84LRRK2 | |
| SCHEMBL174642 | 0.72 | PDPK1 (0.48) | AXLAURKAPARP1GPR84LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285629-A | 5- [1,2, 4-Oxadiazole ] -6-oxygen-pyrazolopyridine derivative and preparation method and application thereof | 中南大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119285629-A | 5- [1,2, 4-Oxadiazole ] -6-oxygen-pyrazolopyridine derivative and preparation method and application thereof | 中南大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-119219630-A | 1H-pyrazolo [3,4-B ] pyridine-3-carbonitrile crystal form A and preparation method thereof | 合肥菁科生物科技有限公司 | 2024-12-31 | — | — | CN | disclosed |