SCHEMBL31304875

SCHEMBL31304875

COCc1cc(B2OC(C)(C)C(C)(C)O2)cc2c1NC(=O)C2

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.31
LIPG Q9Y5X9 5/20 0.31
ROCK1 Q13464 1/20 0.31
LPL P06858 4/20 0.31
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18189371 0.87 LIPG (0.35) LIPGROCK1LPL
SCHEMBL18189286 0.81 CSF1R (0.37) CSF1RLIPGLPLBACE1
SCHEMBL18189401 0.79 GRIA1 (0.38) LIPGLPL
SCHEMBL18189549 0.78 AHR (0.43) LIPGROCK1LPL
SCHEMBL15288616 0.78 LIPG (0.40) LIPGROCK1LPLBACE1
SCHEMBL18189322 0.74 LIPG (0.32) LIPGLPL
SCHEMBL18189341 0.74 LIPG (0.34) LIPGLPL
SCHEMBL31304893 0.74 TDP2 (0.40)
SCHEMBL20111129 0.74 GRIA1 (0.43) LIPGLPL
SCHEMBL20112974 0.71 CSF1R (0.30) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739694-A2 MACROCYCLIC COMPOUNDS AND USE AS TYK2 INHIBITORS Blossomhill Therapeutics, Inc. (US) 2026-05-13 EP disclosed
WO-2025010294-A2 MACROCYCLIC COMPOUNDS AND USE AS TYK2 INHIBITORS BLOSSOMHILL THERAPEUTICS, INC. (US) 2025-01-09 WO disclosed