Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039831 | 0.92 | SIRT5 (0.61) | KLK7KLK5MAPTSIRT5SIRT2 | |
| SCHEMBL17039855 | 0.89 | SIRT5 (0.57) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL17039813 | 0.89 | SIRT2 (0.59) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL17750718 | 0.89 | SIRT5 (0.57) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL31045343 | 0.86 | SIRT2 (0.56) | MAPTSIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL30064541 | 0.86 | MAPT (0.62) | KLK7KLK5MAPT | |
| SCHEMBL29813489 | 0.85 | MAPT (0.56) | KLK7KLK5MAPTSIRT5SIRT2 | |
| SCHEMBL30668140 | 0.85 | KLK7 (0.57) | KLK7KLK5MAPT | |
| SCHEMBL13599678 | 0.83 | L3MBTL1 (0.59) | KLK7KLK5MAPTSIRT5SIRT2 | |
| SCHEMBL16847749 | 0.83 | SIRT5 (0.51) | KLK7KLK5MAPTSIRT5SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |