Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305700 | 0.74 | KDM4E (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31300632 | 0.72 | NPC1 (0.49) | NPC1F10PTGER4KLKB1KDM4E | |
| SCHEMBL20604916 | 0.72 | NPC1 (0.49) | NPC1F10PTGER4KLKB1KDM4E | |
| SCHEMBL15050722 | 0.71 | NPC1 (0.40) | NPC1MAPK8KLKB1F11ALDH1A1 | |
| SCHEMBL17782347 | 0.71 | NR4A2 (0.62) | NPC1KDM4EALDH1A1HSD17B10NPSR1 | |
| SCHEMBL14158206 | 0.71 | ELANE (0.50) | NPC1PTGER4KDM4EALDH1A1HPGD | |
| SCHEMBL14709938 | 0.69 | ALDH1A1 (0.53) | NPC1F11KDM4EALDH1A1HPGD | |
| SCHEMBL1244925 | 0.68 | MAPT (0.37) | NPC1KLKB1F11KDM4EHSD17B10 | |
| SCHEMBL31414520 | 0.68 | NPC1 (0.48) | NPC1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL3077373 | 0.68 | NPC1 (0.39) | NPC1PTGER4KLKB1F11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431394-A | Pyridazinone derivatives and medical application thereof | 杭州百新生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |