Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394653 | 1.00 | PTPN1 (0.77) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL669210 | 0.91 | PTPN1 (0.72) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| Warangalone SCHEMBL571534 | 0.89 | PTPN1 (0.86) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| Auriculasin SCHEMBL30288227 | 0.87 | PTPN1 (1.00) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| Auriculasin SCHEMBL25989454 | 0.87 | PTPN1 (1.00) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| Auriculasin SCHEMBL29378888 | 0.87 | PTPN1 (1.00) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL11911700 | 0.85 | PTPN1 (0.81) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL30643540 | 0.83 | PTPN1 (0.83) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL15942840 | 0.82 | PTPN1 (0.77) | PTPN1CYP3A4MAPTMAPK1MEN1 | |
| Osajin SCHEMBL571689 | 0.82 | PTPN1 (1.00) | PTPN1CYP3A4MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009927-A1 | Anti-Inflammatory and Anti-Allergy Extracts from Nettle | HERBALSCIENCE GROUP LLC (US) | 2010-01-14 | — | — | US | disclosed |