Osajin

Osajin

SCHEMBL571689

CC(C)=CCc1c2c(c3occ(-c4ccc(O)cc4)c(=O)c3c1O)C=CC(C)(C)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 1.00
CYP3A4 P08684 6/20 1.00
MAPT P10636 5/20 1.00
MAPK1 P28482 3/20 1.00
ALDH1A1 P00352 3/20 1.00
MEN1 O00255 3/20 1.00
USP2 O75604 3/20 1.00
ALOX15 P16050 3/20 1.00
KMT2A Q03164 3/20 1.00
HDAC3 O15379 2/20 1.00
TP53 P04637 2/20 1.00
HDAC4 P56524 2/20 1.00
HDAC1 Q13547 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
HDAC7 Q8WUI4 2/20 1.00
HDAC2 Q92769 2/20 1.00
HDAC10 Q969S8 2/20 1.00
HDAC11 Q96DB2 2/20 1.00
HDAC8 Q9BY41 2/20 1.00
HDAC6 Q9UBN7 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Osajin SCHEMBL22093541 0.97 PTPN1 (0.95) PTPN1CYP3A4MAPTMAPK1ALDH1A1
Osajin SCHEMBL27659828 0.96 PTPN1 (0.93) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL18906967 0.94 PTPN1 (0.88) PTPN1CYP3A4MAPTMAPK1ALDH1A1
Warangalone SCHEMBL571534 0.93 PTPN1 (0.86) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL11911697 0.91 CYP3A4 (0.84) PTPN1CYP3A4MAPTMAPK1ALDH1A1
Pomiferin SCHEMBL8059171 0.90 CYP3A4 (1.00) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL22108474 0.90 PTPN1 (0.81) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL24305393 0.89 CYP3A4 (0.81) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL24305356 0.89 CYP3A4 (0.85) PTPN1CYP3A4MAPTMAPK1ALDH1A1
SCHEMBL18906963 0.89 CYP3A4 (0.87) PTPN1CYP3A4MAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082672-A1 METAL (HYDR) OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME CNPHARM CO., LTD. (KR) 2025-03-13 US claimed
EP-4520339-A2 METAL (HYDR)OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Webiotree Co., Ltd. (KR) 2025-03-12 EP claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023182736-A1 MULTI-LAYERED TABLET COMPOSITE FORMULATION AND PREPARATION METHOD THEREFOR 주식회사 위바이오트리 2023-09-28 WO claimed
US-20230233483-A1 COMPOUND AND METHOD FOR THE TREATMENT OF CORONAVIRUSES APTEEUS (FR) 2023-07-27 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
US-20230040651-A1 METAL (HYDR)OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME WEBIOTREE CO., LTD. (KR) 2023-02-09 US claimed
EP-4091603-A1 METAL (HYDR)OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Webiotree Co., Ltd. (KR) 2022-11-23 EP claimed
US-20220323356-A1 METAL (HYDR)OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME CNPHARM CO., LTD. (KR) 2022-10-13 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
CN-1395573-A Extraction of flavonoids BIOREX HEALTH LTD (AU) 2003-02-05 CN claimed
CN-1376050-A Skin care composition UNILEVER PLC (NL) 2002-10-23 CN claimed
CN-1365620-A Functional food for preventing damage of mobile telephone radiation MI MANTIAN (CN) 2002-08-28 CN claimed
CN-1352935-A Cosmetics composition containing aminophenol derivatives and isoflavone like substance OREAL (FR) 2002-06-12 CN claimed
CN-1347459-A Novel substance originating in basidiomycete culture, process for producing same and use thereof AMINO UP CHEMICAL CO LTD (JP) 2002-05-01 CN claimed
CN-1333681-A Method for reducing blood cholesterol and/or blood triglycerides EASTMAN CHEM CO (US) 2002-01-30 CN claimed
EP-1151295-A1 METHODS OF IDENTIFYING THERAPEUTICALLY EFFECTIVE ANTINEOPLASTIC AGENTS WITH CULTURED CELLS HAVING INTACT CELL MEMBRANES AND CORRESPONDING PRODUCTS Cytovia, Inc. (US) 2001-11-07 EP claimed
CN-1312712-A Therapeutic composition based on flavonoids for use in treatment of tumours with cytotoxic agents L LAB (FR) 2001-09-12 CN claimed
CN-1310610-A Pharmaceutical composition for preventing and treating radiation mucositis and chemical mucositis LAFON LABOR (FR) 2001-08-29 CN claimed
WO-2000045165-A1 METHODS OF IDENTIFYING THERAPEUTICALLY EFFECTIVE ANTINEOPLASTIC AGENTS WITH CULTURED CELLS HAVING INTACT CELL MEMBRANES AND CORRESPONDING PRODUCTS CYTOVIA, INC. (US) 2000-08-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040651-A1 METAL (HYDR)OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME HAAO, HAO2, HAO1 PTPN1 566/4885CYP3A4 99/4885MAPT 406/4885
US-20250082672-A1 METAL (HYDR) OXIDE COMPOSITE COMPRISING POORLY SOLUBLE DRUG, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME HAAO, HAO2, HAO1 PTPN1 566/4885CYP3A4 99/4885MAPT 406/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB PTPN1 4752/4885CYP3A4 3571/4885MAPT 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.