Warangalone — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN1	P18031	8/20	0.86

▸	CYP3A4	P08684	6/20	0.86

▸	MAPT	P10636	5/20	0.86

▸	MAPK1	P28482	3/20	0.86

▸	MEN1	O00255	3/20	0.86

▸	USP2	O75604	3/20	0.86

▸	ALOX15	P16050	3/20	0.86

▸	KMT2A	Q03164	3/20	0.86

▸	ALDH1A1	P00352	3/20	0.86

▸	HDAC3	O15379	2/20	0.86

▸	TP53	P04637	2/20	0.86

▸	HDAC4	P56524	2/20	0.86

▸	HDAC1	Q13547	2/20	0.86

▸	SMN1; SMN2	Q16637	2/20	0.86

▸	HDAC7	Q8WUI4	2/20	0.86

▸	HDAC2	Q92769	2/20	0.86

▸	HDAC10	Q969S8	2/20	0.86

▸	HDAC11	Q96DB2	2/20	0.86

▸	HDAC8	Q9BY41	2/20	0.86

▸	HDAC6	Q9UBN7	2/20	0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11911700	0.94	PTPN1 (0.81)	PTPN1CYP3A4MAPTMAPK1MEN1
Osajin SCHEMBL571689	0.93	PTPN1 (1.00)	PTPN1CYP3A4MAPTMAPK1MEN1
SCHEMBL15942840	0.91	PTPN1 (0.77)	PTPN1CYP3A4MAPTMAPK1MEN1
Osajin SCHEMBL22093541	0.90	PTPN1 (0.95)	PTPN1CYP3A4MAPTMAPK1MEN1
Auriculasin SCHEMBL25989454	0.90	PTPN1 (1.00)	PTPN1CYP3A4MAPTMAPK1MEN1
Auriculasin SCHEMBL29378888	0.90	PTPN1 (1.00)	PTPN1CYP3A4MAPTMAPK1MEN1
Auriculasin SCHEMBL30288227	0.90	PTPN1 (1.00)	PTPN1CYP3A4MAPTMAPK1MEN1
Osajin SCHEMBL27659828	0.89	PTPN1 (0.93)	PTPN1CYP3A4MAPTMAPK1MEN1
SCHEMBL29394653	0.89	PTPN1 (0.77)	PTPN1CYP3A4MAPTMAPK1MEN1
SCHEMBL3130630	0.89	PTPN1 (0.77)	PTPN1CYP3A4MAPTMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9822125-B2	Benzopyran compounds as melanogenesis modifiers and uses thereof	NEW YORK UNIVERSITY (US)	2017-11-21	—	—	US	claimed
US-20150030551-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY	2015-01-29	—	—	US	claimed
US-8802722-B2	Benzopyran compounds as melanogenesis modifiers and uses thereof	NEW YORK UNIVERSITY (US)	2014-08-12	—	—	US	claimed
WO-2012103493-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY (US)	2012-08-02	—	—	WO	claimed
US-20120196926-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY	2012-08-02	—	—	US	claimed
US-20240016777-A1	COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	2024-01-18	—	—	US	disclosed
US-20240016777-A1	COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	2024-01-18	—	—	US	disclosed
US-20240016777-A1	COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS	BETH ISRAEL DEACONESS MEDICAL CENTER, INC.	2024-01-18	—	—	US	disclosed
US-9822125-B2	Benzopyran compounds as melanogenesis modifiers and uses thereof	NEW YORK UNIVERSITY (US)	2017-11-21	—	—	US	disclosed
US-9822125-B2	Benzopyran compounds as melanogenesis modifiers and uses thereof	NEW YORK UNIVERSITY (US)	2017-11-21	—	—	US	disclosed
US-9822125-B2	Benzopyran compounds as melanogenesis modifiers and uses thereof	NEW YORK UNIVERSITY (US)	2017-11-21	—	—	US	disclosed
CN-107233338-A	Climb application of the trifoliate jewelvine isoflavones in prevention and/or treatment uterine neck cancer drug is prepared	暨南大学	2017-10-10	—	—	CN	disclosed
EP-2598150-A2	COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS	The Hospital For Sick Children (CA)	2013-06-05	—	—	EP	disclosed
US-20120196926-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY	2012-08-02	—	—	US	disclosed
US-20120196926-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY	2012-08-02	—	—	US	disclosed
US-20120196926-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY	2012-08-02	—	—	US	disclosed
WO-2012103493-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	NEW YORK UNIVERSITY (US)	2012-08-02	—	—	WO	disclosed
WO-2012018643-A2	COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS	THE HOSPITAL FOR SICK CHILDREN (CA)	2012-02-09	—	—	WO	disclosed
US-20110301105-A1	COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS	THE HOSPITAL FOR SICK CHILDREN (CA)	2011-12-08	—	—	US	disclosed
WO-2010039679-A1	COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS	THE HOSPITAL FOR SICK CHILDREN (CA)	2010-04-08	—	—	WO	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20240016777-A1	COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS	THPO, SERPINB1, SERPINC1	PTPN1 1318/4885CYP3A4 1420/4885MAPT 2717/4885
US-20110301105-A1	COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS	MKI67, KRT18, PROX1	PTPN1 3544/4885CYP3A4 4005/4885MAPT 2714/4885
US-20150030551-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	TYR, MITF, MC1R	PTPN1 3805/4885CYP3A4 839/4885MAPT 4033/4885
US-20120196926-A1	BENZOPYRAN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF	TYR, MITF, MC1R	PTPN1 3805/4885CYP3A4 839/4885MAPT 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.