Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988063 | 1.00 | TDP1 (0.53) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL3143646 | 0.79 | TDP1 (0.53) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30469661 | 0.79 | TDP1 (0.53) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24366369 | 0.79 | TDP1 (0.53) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL18015411 | 0.79 | TDP1 (0.53) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL17199629 | 0.76 | TDP1 (0.50) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL13490344 | 0.75 | TDP1 (0.56) | TDP1CASP3SENP8SENP7SENP6 | |
| SCHEMBL2643410 | 0.72 | ACMSD (0.46) | TDP1JAK2JAK1JAK3TBK1 | |
| SCHEMBL171525 | 0.72 | SIGMAR1 (0.44) | — | |
| SCHEMBL29936063 | 0.72 | SIGMAR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004785-A | Compounds and compositions for the treatment of diseases associated with STING activity | 诺华制药股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-112823036-B | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-11-08 | — | — | CN | disclosed |