Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.59 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307745 | 0.89 | CYP19A1 (0.73) | CYP19A1CYP11B1CYP11B2HMOX1TBXAS1 | |
| SCHEMBL31307685 | 0.88 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2HMOX1TBXAS1 | |
| SCHEMBL31307775 | 0.87 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2HMOX1TBXAS1 | |
| SCHEMBL7477480 | 0.86 | HMOX1 (0.75) | CYP19A1CYP11B1CYP11B2HMOX1TBXAS1 | |
| SCHEMBL8865557 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA | |
| Bromide SCHEMBL27949880 | 0.84 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA | |
| Bromide SCHEMBL27949879 | 0.84 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA | |
| SCHEMBL31307703 | 0.83 | CYP19A1 (0.68) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA | |
| SCHEMBL11707006 | 0.83 | FNTA (0.57) | CYP19A1CYP11B1CYP11B2HMOX1TBXAS1 | |
| SCHEMBL31307726 | 0.82 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2TBXAS1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994022-A | Preparation method of 1-methyl-4-phenyl ether derivative and application of non-classical antibacterial activity | 中国人民解放军军事科学院军事医学研究院 | 2024-11-22 | — | — | CN | claimed |
| CN-118994022-A | Preparation method of 1-methyl-4-phenyl ether derivative and application of non-classical antibacterial activity | 中国人民解放军军事科学院军事医学研究院 | 2024-11-22 | — | — | CN | disclosed |