Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 5/20 | 0.56 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.56 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibenzoylmethane SCHEMBL3478420 | 0.87 | CYP3A4 (0.57) | PLOD2PLOD3PLOD1KDRKDM4E | |
| Dibenzoylmethane SCHEMBL28803142 | 0.87 | CYP3A4 (0.57) | PLOD2PLOD3PLOD1KDRKDM4E | |
| Dibenzoylmethane SCHEMBL17022453 | 0.85 | CYP3A4 (0.59) | PLOD2PLOD3PLOD1KDRKDM4E | |
| Dibenzoylmethane SCHEMBL28036057 | 0.85 | CYP3A4 (0.59) | PLOD2PLOD3PLOD1KDRKDM4E | |
| SCHEMBL9630807 | 0.82 | PLOD2 (0.67) | PLOD2PLOD3PLOD1KDM4ECYP1A2 | |
| SCHEMBL10613054 | 0.82 | PLOD2 (0.67) | PLOD2PLOD3PLOD1KDM4ECYP1A2 | |
| SCHEMBL9654173 | 0.82 | PLOD2 (0.67) | PLOD2PLOD3PLOD1KDM4ECYP1A2 | |
| Phenanthroline SCHEMBL22445053 | 0.82 | KDM4E (0.47) | PLOD2PLOD3PLOD1KDM4EEGLN1 | |
| SCHEMBL523476 | 0.81 | PLOD2 (0.69) | PLOD2PLOD3PLOD1KDM4ECYP1A2 | |
| Phenanthroline SCHEMBL3137741 | 0.80 | MEN1 (0.47) | PLOD2PLOD3PLOD1KDM4EEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642996-B2 | Method of driving an organic electroluminescent device comprising a phosphorescent light emitter | ISIS INNOVATION LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20060152165-A1 | Method of driving an electroluminescent device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2006-07-13 | — | — | US | disclosed |
| EP-1423838-A2 | METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE | Isis Innovation Limited (GB) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003021563-A2 | METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE | ISIS INNOVATION LIMITED (GB) | 2003-03-13 | — | — | WO | disclosed |