Dibenzoylmethane

Dibenzoylmethane

SCHEMBL28803142

O=C(CC(=O)c1ccccc1)c1ccccc1.[Eu].c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.57
KDM4E B2RXH2 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
HPGD P15428 2/20 0.57
MAPT P10636 2/20 0.57
ALOX15 P16050 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
CES1 P23141 1/20 0.57
MAPK1 P28482 1/20 0.57
ALDH1A1 P00352 5/20 0.56
PLOD2 O00469 2/20 0.56
CYP2D6 P10635 2/20 0.56
HIF1A Q16665 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
PLOD3 O60568 1/20 0.56
CYP2C9 P11712 1/20 0.56
PLOD1 Q02809 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL3478420 1.00 CYP3A4 (0.57) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL17022453 0.98 CYP3A4 (0.59) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL28036057 0.98 CYP3A4 (0.59) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL1969521 0.87 LMNA (0.62) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL27683419 0.87 LMNA (0.62) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Phenanthroline SCHEMBL3130843 0.87 PLOD2 (0.56) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL2479758 0.85 LMNA (0.64) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL27729815 0.85 LMNA (0.64) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL2363871 0.85 ADORA3 (0.46) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A
Dibenzoylmethane SCHEMBL28343728 0.84 LMNA (0.62) CYP3A4KDM4ESMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103078056-A Light-blind organic ultraviolet detection device based on rare earth complex UNIV BEIJING JIAOTONG 2013-05-01 CN disclosed