Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1500059 | 0.86 | PIK3CG (0.55) | PIK3CGMAP3K5MCHR1APPGAA | |
| SCHEMBL31309514 | 0.83 | PIK3CG (0.51) | PIK3CGMAP3K5MCHR1APPGAA | |
| SCHEMBL516957 | 0.79 | PIK3CG (0.55) | PIK3CGMAP3K5MCHR1APPGAA | |
| SCHEMBL31528488 | 0.77 | KDM4E (0.40) | MCHR1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1500308 | 0.76 | PIK3CG (0.47) | PIK3CGMAP3K5APPGAARAB9A | |
| SCHEMBL1500284 | 0.73 | RAB9A (0.45) | PIK3CGMAP3K5APPGAARAB9A | |
| SCHEMBL418021 | 0.72 | PIK3CG (0.60) | PIK3CGMAP3K5APPGAARAB9A | |
| SCHEMBL23534439 | 0.69 | MAP3K5 (0.47) | PIK3CGMAP3K5APPGAARAB9A | |
| SCHEMBL31309502 | 0.69 | PIK3CG (0.51) | PIK3CGMAP3K5MCHR1APPGAA | |
| SCHEMBL1500263 | 0.69 | PIK3CG (0.51) | PIK3CGMAP3K5APPGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731207-A2 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025006293-A2 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2025-01-02 | — | — | WO | disclosed |