Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985943 | 0.81 | TLR9 (0.47) | KDM4ENPC1RAB9AMCHR1HDAC4 | |
| SCHEMBL12498191 | 0.80 | HDAC4 (0.47) | KDM4ENPC1RAB9AMETTL3HDAC4 | |
| SCHEMBL31528637 | 0.78 | MCHR1 (0.34) | KDM4ENPC1RAB9AMCHR1HDAC4 | |
| SCHEMBL20985954 | 0.77 | METTL3 (0.46) | KDM4ENPC1RAB9AMETTL3POLB | |
| SCHEMBL31309594 | 0.77 | PIK3CG (0.51) | KDM4ENPC1RAB9AMCHR1ALDH1A1 | |
| SCHEMBL1426603 | 0.74 | HDAC1 (0.50) | KDM4ENPC1RAB9AMETTL3POLB | |
| SCHEMBL31528509 | 0.74 | METTL3 (0.44) | KDM4ENPC1RAB9AMETTL3POLB | |
| SCHEMBL31528556 | 0.73 | NPC1 (0.44) | KDM4ENPC1RAB9AMETTL3POLB | |
| SCHEMBL13633452 | 0.70 | PIK3CG (0.56) | KDM4ENPC1RAB9AMETTL3POLB | |
| SCHEMBL1426874 | 0.70 | METTL3 (0.46) | KDM4ENPC1RAB9AMETTL3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077671-A1 | POLYSUBSTITUTED ARYL DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2025-04-17 | — | — | WO | disclosed |