Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.38 |
| ▸ | PARP1 | P09874 | 8/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468004 | 0.72 | MAP2K1 (0.60) | MAP2K1PARP10PARP1PARP11PDPK1 | |
| SCHEMBL10152934 | 0.69 | — | — | |
| SCHEMBL3495344 | 0.68 | HTR1D (0.40) | PARP1DRD2DRD4 | |
| SCHEMBL29850336 | 0.68 | PNMT (0.46) | PARP1 | |
| SCHEMBL4382926 | 0.67 | NOTUM (0.42) | MAP2K1PARP10PARP1PARP11CRBN | |
| SCHEMBL16064614 | 0.64 | CD44 (0.46) | MEN1KMT2A | |
| SCHEMBL8343856 | 0.64 | PARP1 (0.33) | PARP1MAPTDAO | |
| SCHEMBL22926224 | 0.64 | PARP1 (0.39) | PARP10PARP1PARP11PDPK1MAPT | |
| SCHEMBL4723110 | 0.64 | PARP1 (0.47) | PARP1PDPK1MAPT | |
| SCHEMBL917625 | 0.64 | PARP1 (0.43) | PARP1PDPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002493-A1 | PYRIDONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | Nanjing China-australia Institute Of Translational Medicine Co., Ltd. (CN) | 2025-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002493-A1 | PYRIDONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | XIAP, BIRC5, BIRC2 | MAP2K1 296/4885PARP10 954/4885PARP1 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.