Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.40 |
| ▸ | HTR1B | P28222 | 8/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180561 | 0.89 | HTR1D (0.39) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL29168535 | 0.80 | HTR1D (0.38) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL18856176 | 0.76 | PIK3CD (0.47) | AHRADRB1HTR6PARP1PIK3CD | |
| SCHEMBL7617146 | 0.70 | PNMT (0.49) | HTR1DHTR1B | |
| SCHEMBL28928496 | 0.69 | HTR1D (0.36) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL7872035 | 0.69 | NOTUM (0.44) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL2321560 | 0.69 | AURKA (0.42) | — | |
| SCHEMBL2398840 | 0.68 | AHR (0.52) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL31310076 | 0.68 | MAP2K1 (0.40) | PARP1DRD2DRD4 | |
| SCHEMBL16382753 | 0.68 | CFB (0.35) | AHRPARP1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143103-A | Continuous preparation method of pyrroloindoline/furan indoline compound | 浙江工业大学 | 2023-12-01 | — | — | CN | claimed |
| CN-112939749-A | Green bromination method | 香港科技大学 | 2021-06-11 | — | — | CN | claimed |
| EP-1412335-A4 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2004-11-17 | — | — | EP | claimed |
| EP-1412335-A2 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-06-12 | — | — | US | claimed |
| WO-2003002491-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α, β-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-01-09 | — | — | WO | claimed |
| CN-117143103-B | Continuous preparation method of pyrroloindoline/furan indoline compound | 浙江工业大学 | 2025-10-21 | — | — | CN | disclosed |
| CN-117143103-B | Continuous preparation method of pyrroloindoline/furan indoline compound | 浙江工业大学 | 2025-10-21 | — | — | CN | disclosed |
| US-12448398-B2 | Semi-synthetic analogues of epipolythiodioxopiperazine alkaloids | OHIO STATE INNOVATION FOUNDATION (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250084103-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-03-13 | — | — | US | disclosed |
| US-12180228-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-12-31 | — | — | US | disclosed |
| CN-118894909-B | Preparation method of natural cyclic peptide petrichorin C | 深圳乾延药物研发科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118894909-A | Preparation method of natural cyclic peptide petrichorin C | 深圳乾延药物研发科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-6784323-B2 | Enantioselective transformation of α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| EP-1412335-A2 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030220507-A1 | Enantioselective transformation of alpha,beta-unsaturated ketones using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-11-27 | — | — | US | disclosed |
| WO-2003078450-A2 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| WO-2003047740-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α,β-UNSATURATED KETONES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-06-12 | — | — | WO | disclosed |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-06-12 | — | — | US | disclosed |
| WO-2003002491-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α, β-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220507-A1 | Enantioselective transformation of alpha,beta-unsaturated ketones using chiral organic catalysts | HACL2, EBP, MED1 | HTR1D 1065/4885HTR1B 1607/4885AHR 591/4885 |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | ALDH1A1, GAR1, ALDH1B1 | HTR1D 327/4885HTR1B 739/4885AHR 470/4885 |
| US-20250084103-A1 | COMPOUNDS, CONJUGATES, AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES AND USES THEREOF | DNPEP, DHPS, NPEPPS | HTR1D 2328/4885HTR1B 555/4885AHR 699/4885 |
| US-12448398-B2 | Semi-synthetic analogues of epipolythiodioxopiperazine alkaloids | EHMT1, EHMT2, KMT5A | HTR1D 3736/4885HTR1B 3663/4885AHR 1475/4885 |
| US-12180228-B2 | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof | DNPEP, DHPS, NPEPPS | HTR1D 2328/4885HTR1B 555/4885AHR 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.