Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.80 |
| ▸ | GLS | O94925 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22006503 | 0.88 | KCNH2 (0.80) | KCNH2GLS | |
| SCHEMBL18945962 | 0.86 | GLS (0.81) | KCNH2GLS | |
| SCHEMBL20373637 | 0.85 | GLS (1.00) | KCNH2GLS | |
| SCHEMBL22006876 | 0.83 | GLS (0.77) | KCNH2GLS | |
| SCHEMBL20373216 | 0.82 | GLS (0.81) | KCNH2GLS | |
| SCHEMBL18946049 | 0.81 | GLS (0.85) | KCNH2GLS | |
| SCHEMBL22193574 | 0.80 | GLS (0.89) | KCNH2GLS | |
| SCHEMBL29462506 | 0.79 | GLS (0.78) | KCNH2GLS | |
| SCHEMBL22193563 | 0.78 | GLS (0.75) | KCNH2GLS | |
| SCHEMBL19116106 | 0.76 | GLS (0.70) | KCNH2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264128-A | Thiadiazole and pyridazine parent nucleus compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2025-01-07 | — | — | CN | disclosed |