SCHEMBL31310382

SCHEMBL31310382

COc1ccc(C=C2S/C(=N\c3ccc(S(N)(=O)=O)cc3)N(C3CCCCC3)C2=O)cc1OC

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 9/20 0.54
▸ MGAM O43451 8/20 0.54
▸ CA12 O43570 8/20 0.54
▸ CA1 P00915 8/20 0.54
▸ CA2 P00918 8/20 0.54
▸ FAAH O00519 3/20 0.53
▸ PPARG P37231 4/20 0.49
▸ PPARD Q03181 4/20 0.49
▸ PPARA Q07869 2/20 0.49
▸ S1PR1 P21453 1/20 0.47
▸ S1PR3 Q99500 1/20 0.47
▸ PTGS2 P35354 2/20 0.47
▸ PTGS1 P23219 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31310529 0.94 PPARG (0.52) CA9MGAMCA12CA1CA2
SCHEMBL31310426 0.91 CA2 (0.52) CA9MGAMCA12CA1CA2
SCHEMBL31310359 0.89 CA9 (0.70) CA9MGAMCA12CA1CA2
SCHEMBL31310443 0.88 CA2 (0.60) CA9MGAMCA12CA1CA2
SCHEMBL31310324 0.87 CA12 (0.56) CA9MGAMCA12CA1CA2
SCHEMBL31310436 0.86 FAAH (0.60) CA9MGAMCA12CA1CA2
SCHEMBL31310369 0.85 FAAH (0.51) CA9MGAMCA12CA1CA2
SCHEMBL31310312 0.85 FAAH (0.58) CA9MGAMCA12CA1CA2
SCHEMBL31310343 0.85 S1PR1 (0.56) CA9MGAMCA12CA1CA2
SCHEMBL31310357 0.85 FAAH (0.49) CA9MGAMCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731614-A1 THIAZOLIDINONES AS ANTIVIRAL AGENTS UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2026-04-29 — — EP claimed
WO-2025003911-A1 THIAZOLIDINONES AS ANTIVIRAL AGENTS UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2025-01-02 — — WO claimed
EP-4731614-A1 THIAZOLIDINONES AS ANTIVIRAL AGENTS UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2026-04-29 — — EP disclosed
WO-2025003911-A1 THIAZOLIDINONES AS ANTIVIRAL AGENTS UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2025-01-02 — — WO disclosed
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