SCHEMBL3486076

SCHEMBL3486076

CC12C=NC=NC1=NC=N2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223567 1.00
Pyrimidine SCHEMBL28092233 0.88
SCHEMBL7892671 0.71
SCHEMBL4440463 0.70
SCHEMBL28185868 0.70
SCHEMBL31310667 0.68
SCHEMBL28131368 0.65
SCHEMBL28154865 0.60
SCHEMBL19286839 0.55
SCHEMBL18569705 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297241-B2 Method to engineer transplantable human tissues THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-13 US claimed
US-20220235104-A1 NOVEL METHOD TO ENGINEER TRANSLANTABLE HUMAN TISSUES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-28 US claimed
EP-4720294-A2 MODIFIED UNC13A OLIGONUCLEOTIDES Quralis Corporation (US) 2026-04-08 EP disclosed
US-12297241-B2 Method to engineer transplantable human tissues THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-13 US disclosed
WO-2025097174-A1 SPATIALLY ENCAPSULATED DNA ENCODED LIBRARIES AND METHODS OF SCREENING SAME OM THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-119790152-A Treatment of neurological disorders using modulators of UNC13A gene transcripts 奎里斯公司 2025-04-08 CN disclosed
CN-119522282-A Splice transducer antisense oligonucleotides with modified backbone chemistry 奎里斯公司 2025-02-25 CN disclosed
CN-119452086-A GAPMER antisense oligonucleotides with modified backbone chemistry 奎里斯公司 2025-02-14 CN disclosed
WO-2024249791-A2 MODIFIED UNC13A OLIGONUCLEOTIDES QURALIS CORPORATION (US) 2024-12-05 WO disclosed
US-20240368604-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME NOGRA PHARMA LTD (IE) 2024-11-07 US disclosed
EP-4441224-A1 GAPMER ANTISENSE OLIGONUCLEOTIDES WITH MODIFIED BACKBONE CHEMISTRIES Quralis Corporation (US) 2024-10-09 EP disclosed
EP-0215942-B1 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD ANTIVIRALS INC (US) 1995-07-12 EP disclosed
EP-0639582-A2 Polynucleotide assay reagent and method ANTIVIRALS INC. (US) 1995-02-22 EP disclosed
EP-0216860-B1 STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS SUMMERTON, James (US) 1992-10-28 EP disclosed
EP-0216860-A4 STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. SUMMERTON JAMES (US) 1989-02-22 EP disclosed
EP-0215942-A4 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. SUMMERTON JAMES 1988-08-23 EP disclosed
EP-0216860-A1 STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. SUMMERTON JAMES (US) 1987-04-08 EP disclosed
EP-0215942-A1 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. SUMMERTON JAMES 1987-04-01 EP disclosed
WO-1986005518-A1 STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS SUMMERTON JAMES 1986-09-25 WO disclosed
WO-1986005519-A1 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD SUMMERTON JAMES 1986-09-25 WO disclosed