Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129220 | 0.86 | PDE4A (0.38) | PDE4BBACE1 | |
| SCHEMBL3123548 | 0.85 | F7 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3117589 | 0.82 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3131094 | 0.80 | PDE4A (0.47) | PDE4B | |
| SCHEMBL3131223 | 0.80 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL3123596 | 0.79 | MAPT (0.48) | L3MBTL1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3120994 | 0.79 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL3133557 | 0.78 | PDE4A (0.51) | PDE4B | |
| SCHEMBL3133274 | 0.78 | PDE4A (0.54) | PDE4B | |
| SCHEMBL3122747 | 0.77 | PDE4B (0.47) | L3MBTL1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |