Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133557 | 0.97 | PDE4A (0.51) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3131094 | 0.95 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3120556 | 0.84 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3118142 | 0.83 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7317892 | 0.80 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8285881 | 0.80 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3128689 | 0.80 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3122747 | 0.79 | PDE4B (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL5823404 | 0.78 | PDE4A (0.62) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3131098 | 0.78 | L3MBTL1 (0.42) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |