Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123550 | 0.87 | F2 (0.42) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3129223 | 0.87 | PDE4B (0.40) | MAPTMEN1KMT2A | |
| SCHEMBL3117592 | 0.83 | MAPT (0.58) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3123599 | 0.80 | MAPT (0.52) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3131100 | 0.80 | POLB (0.44) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3121001 | 0.80 | GPX4 (0.44) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3131230 | 0.79 | KDM4E (0.40) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL3133279 | 0.78 | POLB (0.51) | ALDH1A1MAPTPOLB | |
| SCHEMBL3122756 | 0.78 | PDE4B (0.45) | ALDH1A1MAPTGAAKDM4ETDP1 | |
| SCHEMBL3133564 | 0.78 | POLB (0.48) | ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |