Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25695223 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30464966 | 0.82 | MPL (0.66) | ALDH1A1MAPTKDM4ECYP3A4HPGD | |
| SCHEMBL10120712 | 0.82 | ALDH1A1 (0.80) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25280365 | 0.82 | MPL (0.66) | ALDH1A1MAPTKDM4ECYP3A4HPGD | |
| SCHEMBL31311278 | 0.81 | MPL (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31311372 | 0.79 | ADORA2A (0.50) | ALDH1A1MAPTCYP1A2MAPK1MEN1 | |
| SCHEMBL31311233 | 0.78 | MPL (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31311397 | 0.78 | MPL (0.66) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL234287 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL599968 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |