Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.42 |
| ▸ | RORB | Q92753 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311302 | 0.88 | MPL (0.47) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL25280365 | 0.86 | MPL (0.66) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL30464966 | 0.86 | MPL (0.66) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL28651159 | 0.86 | MPL (0.50) | MPLADORA1ALOX15HSD17B10KDM4E | |
| SCHEMBL31311278 | 0.84 | MPL (0.52) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL31311397 | 0.82 | MPL (0.66) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL12495409 | 0.80 | HTT (0.55) | ADORA1ADORA2AALOX15HSD17B10KDM4E | |
| SCHEMBL31311334 | 0.78 | MPL (0.47) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL31311151 | 0.78 | ALDH1A1 (0.62) | MPLADORA1ADORA2AALOX15HSD17B10 | |
| SCHEMBL25695223 | 0.78 | ALDH1A1 (0.62) | MPLADORA1ADORA2AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |