Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 13/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311299 | 0.95 | ALOX12 (0.37) | MAPTALOX12ALOX15MEN1KMT2A | |
| SCHEMBL31311320 | 0.90 | ALOX15 (0.46) | MAPTALOX12ALOX15KDM4EMEN1 | |
| SCHEMBL31311207 | 0.89 | ALOX12 (0.37) | MAPTALOX12ALOX15MEN1KMT2A | |
| SCHEMBL31311313 | 0.88 | MAPT (0.42) | MAPTALOX12ALOX15KDM4EMEN1 | |
| SCHEMBL31311301 | 0.84 | ALOX12 (0.47) | MAPTALOX12ALOX15KDM4EMEN1 | |
| SCHEMBL31311230 | 0.84 | MAPT (0.38) | MAPTALOX12ALOX15KDM4EMEN1 | |
| SCHEMBL31311307 | 0.84 | MAPT (0.38) | MAPTALOX12ALOX15KDM4EMEN1 | |
| SCHEMBL31311286 | 0.83 | ALOX12 (0.39) | MAPTALOX12ALOX15MEN1KMT2A | |
| SCHEMBL31311260 | 0.81 | PTGS1 (0.39) | MAPTALOX12ALOX15MEN1KMT2A | |
| SCHEMBL31311191 | 0.79 | ALOX15 (0.51) | MAPTALOX12ALOX15KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |