Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 18/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311240 | 0.94 | ALOX12 (0.49) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311191 | 0.94 | ALOX15 (0.51) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL25235861 | 0.92 | ALOX12 (0.53) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311215 | 0.92 | ALOX12 (0.57) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL30464958 | 0.92 | ALOX12 (0.53) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311162 | 0.91 | ALOX12 (0.51) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311333 | 0.90 | ALOX12 (0.54) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311203 | 0.89 | ALOX12 (0.49) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311235 | 0.89 | ALOX12 (0.49) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL31311365 | 0.88 | ALOX12 (0.52) | ALOX12ALOX15ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |