Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313781 | 0.82 | FFAR1 (0.33) | FFAR1MAPK1 | |
| SCHEMBL27166678 | 0.80 | FFAR1 (0.34) | FFAR1MAPK1 | |
| SCHEMBL31115852 | 0.80 | FFAR1 (0.34) | FFAR1MAPK1 | |
| SCHEMBL24002151 | 0.79 | MAPK1 (0.38) | FFAR1MAPK1 | |
| SCHEMBL600252 | 0.78 | P2RX7 (0.32) | FFAR1MAPK1 | |
| SCHEMBL31115784 | 0.78 | KLKB1 (0.37) | FFAR1MAPK1 | |
| SCHEMBL24009400 | 0.76 | MAPK1 (0.35) | FFAR1MAPK1 | |
| SCHEMBL24010961 | 0.76 | MAPK1 (0.35) | FFAR1MAPK1 | |
| SCHEMBL38661230 | 0.76 | MAPK1 (0.35) | FFAR1MAPK1 | |
| SCHEMBL98872 | 0.75 | FFAR1 (0.53) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727934-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024260929-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-26 | — | — | WO | disclosed |