SCHEMBL31314643

SCHEMBL31314643

CCCCNC(=O)c1ccc(C(=O)c2c(CCCC)oc3ccccc23)cc1

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EYA3 Q99504 3/20 0.72
PTPN1 P18031 1/20 0.72
SIRT3 Q9NTG7 10/20 0.72
TTR P02766 1/20 0.60
NR1H4 Q96RI1 1/20 0.59
KDM5A P29375 1/20 0.59
KDM7A Q6ZMT4 1/20 0.59
ABCB1 P08183 1/20 0.55
SLC22A12 Q96S37 1/20 0.54
THRA P10827 1/20 0.53
THRB P10828 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25389924 0.85 EYA3 (0.82) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL1287970 0.84 EYA3 (1.00) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL28849127 0.84 EYA3 (0.81) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL27992957 0.84 EYA3 (0.80) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL31314614 0.83 EYA3 (0.79) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL31314615 0.83 EYA3 (0.79) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL31314577 0.83 EYA3 (0.79) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL3863077 0.83 EYA3 (0.79) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL9591605 0.81 EYA3 (0.76) EYA3PTPN1SIRT3TTRNR1H4
SCHEMBL5419199 0.81 EYA3 (0.93) EYA3PTPN1SIRT3TTRNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024261504-A1 BENZOFURAN-3-CARBOXYLIC ACID AMIDES AND BENZOFURAN-3- CARBONYL-BENZAMIDES, METHOD FOR THEIR PRODUCTION WITH HIGH SELECTIVITY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PÉCSI TUDOMÁNYEGYETEM (HU) 2024-12-26 WO disclosed