Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | RAF1 | P04049 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26131577 | 1.00 | KDR (0.53) | KDRRAF1GRM4LMNAGAA | |
| SCHEMBL22772368 | 0.84 | LMNA (0.65) | KDRRAF1GRM4LMNAGAA | |
| SCHEMBL24153815 | 0.82 | L3MBTL1 (0.62) | KDRLMNAMAPTRAB9AMEN1 | |
| SCHEMBL21843539 | 0.79 | RET (0.50) | KDRMAPTRAB9AHTTKMT2A | |
| SCHEMBL29063905 | 0.79 | MAPT (0.68) | KDRRAF1GRM4LMNAGAA | |
| SCHEMBL22683074 | 0.79 | MEN1 (0.65) | KDRLMNAMAPTRAB9AMEN1 | |
| SCHEMBL31314816 | 0.79 | MEN1 (0.65) | KDRLMNAMAPTRAB9AMEN1 | |
| SCHEMBL16782084 | 0.77 | KDR (0.69) | KDRRAF1LMNAGAAMAPT | |
| SCHEMBL10220049 | 0.77 | KDR (0.76) | KDRPDK1TRPV1KCNJ5KCNJ3 | |
| SCHEMBL22384734 | 0.77 | KDR (0.68) | KDRRAF1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451675-A | Nicotinamide and benzamide based compounds, conjugates and compositions as inhibitors of translation and transcription related kinases | 普渡研究基金会 | 2025-02-14 | — | — | CN | disclosed |