SCHEMBL31315352

SCHEMBL31315352

Cn1ccc2cc(B3OC(C)(C)C(C)(C)O3)ccc2c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
CSF1R P07333 1/20 0.39
LPL P06858 11/20 0.38
LIPG Q9Y5X9 11/20 0.38
PRMT5 O14744 2/20 0.38
WDR77 Q9BQA1 2/20 0.38
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16651441 1.00 IDO1 (0.40) IDO1TDO2CSF1RLPLLIPG
SCHEMBL19356377 0.89 IDO1 (0.42) IDO1TDO2CSF1RLPLLIPG
SCHEMBL24145842 0.82 IDO1 (0.38) IDO1TDO2CSF1RLPLLIPG
SCHEMBL20808708 0.82 PRMT5 (0.41) IDO1TDO2CSF1RLPLLIPG
SCHEMBL23797296 0.80 IDO1 (0.37) IDO1TDO2CSF1RLPLLIPG
SCHEMBL29807685 0.79 PRKCI (0.46) LPLLIPGCA1CA2CA9
SCHEMBL484221 0.79 PRKCI (0.46) LPLLIPGCA1CA2CA9
SCHEMBL26170011 0.78 IRAK4 (0.44) IDO1TDO2CSF1RLPLLIPG
SCHEMBL6126262 0.78 LPL (0.53) CSF1RLPLLIPGPRMT5WDR77
SCHEMBL25897720 0.76 TNF (0.35) IDO1TDO2CSF1RLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709479-A1 6,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS Amgen Inc. (US) 2026-03-18 EP disclosed
WO-2024233563-A1 6,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS AMGEN INC. (US) 2024-11-14 WO disclosed