Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31756160 | 0.90 | DRD2 (0.43) | DRD2MMP2MMP3MMP9MMP8 | |
| SCHEMBL17848489 | 0.79 | MMP13 (0.44) | DRD2MMP9MMP13SLC6A4SLC6A2 | |
| SCHEMBL17848388 | 0.78 | HTR2A (0.44) | DRD2SLC6A4SLC6A2HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL17848450 | 0.78 | MMP13 (0.42) | DRD2MMP9MMP13SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL31316582 | 0.77 | HTR2A (0.43) | DRD2SLC6A4SLC6A2HTR2CHTR2A | |
| SCHEMBL17848382 | 0.76 | DRD2 (0.46) | DRD2SLC6A4SLC6A2TACR1HTR2C | |
| SCHEMBL19567888 | 0.72 | DRD2 (0.52) | DRD2 | |
| SCHEMBL6819891 | 0.72 | SLC6A4 (0.36) | DRD2SLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL21607088 | 0.71 | SLC6A2 (0.37) | DRD2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25466731 | 0.71 | DRD2 (0.44) | DRD2SLC6A4SLC6A2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025010311-A1 | UREA-CONTAINING AGONISTS OF OREXIN RECEPTOR TYPE 2 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-01-09 | — | — | WO | disclosed |